20 mad scientists who turned against their creations

At io9, Charlie Jane Anders came up with a list of twenty mad scientists who turned against their creations.

One literary mad scientist on the list, which is dominated by movies and television shows:

Marisa Coulter (His Dark Materials by Philip Pullman)

Mrs. Coulter invents a method of controlling the "Dust" that attaches to people — unfortunately, this requires severing children from their Daemons, or basically their souls. When Mrs. Coulter realizes her daughter Lyra is in danger, she dedicates herself to protecting Lyra.

Read about the other mad scientists on the list.

His Dark Materials appears among Amanda Donohoe's six best books.

--Marshal Zeringue